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Imported Lassa fever: a report of 2 cases in Ghana

BACKGROUND: Lassa fever is a potentially fatal acute viral illness caused by Lassa virus which is carried by rodents and is endemic in some West African countries. Importation of emerging infections such as Lassa fever, Ebola Virus Disease and other viral hemorrhagic fevers into non endemic regions...

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Autores principales: Kyei, Nicholas N.A., Abilba, Mark M., Kwawu, Foster K., Agbenohevi, Prince G., Bonney, Joseph H.K., Agbemaple, Thomas K., Nimo-Paintsil, Shirley C., Ampofo, William, Ohene, Sally-Ann, Nyarko, Edward O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448534/
https://www.ncbi.nlm.nih.gov/pubmed/26022703
http://dx.doi.org/10.1186/s12879-015-0956-2
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author Kyei, Nicholas N.A.
Abilba, Mark M.
Kwawu, Foster K.
Agbenohevi, Prince G.
Bonney, Joseph H.K.
Agbemaple, Thomas K.
Nimo-Paintsil, Shirley C.
Ampofo, William
Ohene, Sally-Ann
Nyarko, Edward O.
author_facet Kyei, Nicholas N.A.
Abilba, Mark M.
Kwawu, Foster K.
Agbenohevi, Prince G.
Bonney, Joseph H.K.
Agbemaple, Thomas K.
Nimo-Paintsil, Shirley C.
Ampofo, William
Ohene, Sally-Ann
Nyarko, Edward O.
author_sort Kyei, Nicholas N.A.
collection PubMed
description BACKGROUND: Lassa fever is a potentially fatal acute viral illness caused by Lassa virus which is carried by rodents and is endemic in some West African countries. Importation of emerging infections such as Lassa fever, Ebola Virus Disease and other viral hemorrhagic fevers into non endemic regions is a growing threat particularly as international travel and commitments in resolving conflicts in endemic countries in the West Africa sub-region continue. CASE PRESENTATION: We report the first two recorded imported cases of Lassa fever among Ghanaian Peace keepers in rural Liberia, who became ill while on Peace keeping mission. They were subsequently evacuated to the UN level IV hospital in Accra, where their illnesses were laboratory confirmed. One of the patients recovered with ribavirin treatment and supportive therapy. No secondary clinical cases occurred in Ghana. CONCLUSIONS: Healthcare providers at all levels of care should thus have a high index of suspicion for these infectious diseases and adopt standard infection control measures when treating patients in endemic regions or returning travelers from an endemic region with a febrile illness even of a known etiology.
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spelling pubmed-44485342015-05-30 Imported Lassa fever: a report of 2 cases in Ghana Kyei, Nicholas N.A. Abilba, Mark M. Kwawu, Foster K. Agbenohevi, Prince G. Bonney, Joseph H.K. Agbemaple, Thomas K. Nimo-Paintsil, Shirley C. Ampofo, William Ohene, Sally-Ann Nyarko, Edward O. BMC Infect Dis Case Report BACKGROUND: Lassa fever is a potentially fatal acute viral illness caused by Lassa virus which is carried by rodents and is endemic in some West African countries. Importation of emerging infections such as Lassa fever, Ebola Virus Disease and other viral hemorrhagic fevers into non endemic regions is a growing threat particularly as international travel and commitments in resolving conflicts in endemic countries in the West Africa sub-region continue. CASE PRESENTATION: We report the first two recorded imported cases of Lassa fever among Ghanaian Peace keepers in rural Liberia, who became ill while on Peace keeping mission. They were subsequently evacuated to the UN level IV hospital in Accra, where their illnesses were laboratory confirmed. One of the patients recovered with ribavirin treatment and supportive therapy. No secondary clinical cases occurred in Ghana. CONCLUSIONS: Healthcare providers at all levels of care should thus have a high index of suspicion for these infectious diseases and adopt standard infection control measures when treating patients in endemic regions or returning travelers from an endemic region with a febrile illness even of a known etiology. BioMed Central 2015-05-29 /pmc/articles/PMC4448534/ /pubmed/26022703 http://dx.doi.org/10.1186/s12879-015-0956-2 Text en © Kyei et al.; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Kyei, Nicholas N.A.
Abilba, Mark M.
Kwawu, Foster K.
Agbenohevi, Prince G.
Bonney, Joseph H.K.
Agbemaple, Thomas K.
Nimo-Paintsil, Shirley C.
Ampofo, William
Ohene, Sally-Ann
Nyarko, Edward O.
Imported Lassa fever: a report of 2 cases in Ghana
title Imported Lassa fever: a report of 2 cases in Ghana
title_full Imported Lassa fever: a report of 2 cases in Ghana
title_fullStr Imported Lassa fever: a report of 2 cases in Ghana
title_full_unstemmed Imported Lassa fever: a report of 2 cases in Ghana
title_short Imported Lassa fever: a report of 2 cases in Ghana
title_sort imported lassa fever: a report of 2 cases in ghana
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448534/
https://www.ncbi.nlm.nih.gov/pubmed/26022703
http://dx.doi.org/10.1186/s12879-015-0956-2
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