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Dosage compensation can buffer copy-number variation in wild yeast

Aneuploidy is linked to myriad diseases but also facilitates organismal evolution. It remains unclear how cells overcome the deleterious effects of aneuploidy until new phenotypes evolve. Although laboratory strains are extremely sensitive to aneuploidy, we show here that aneuploidy is common in wil...

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Detalles Bibliográficos
Autores principales:	Hose, James, Yong, Chris Mun, Sardi, Maria, Wang, Zhishi, Newton, Michael A, Gasch, Audrey P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Computational and Systems Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448642/ https://www.ncbi.nlm.nih.gov/pubmed/25955966 http://dx.doi.org/10.7554/eLife.05462

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