Genomic redistribution of GR monomers and dimers mediates transcriptional response to exogenous glucocorticoid in vivo

Glucocorticoids (GCs) are commonly prescribed drugs, but their anti-inflammatory benefits are mitigated by metabolic side effects. Their transcriptional effects, including tissue-specific gene activation and repression, are mediated by the glucocorticoid receptor (GR), which is known to bind as a ho...

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Detalles Bibliográficos
Autores principales: Lim, Hee-Woong, Uhlenhaut, N. Henriette, Rauch, Alexander, Weiner, Juliane, Hübner, Sabine, Hübner, Norbert, Won, Kyoung-Jae, Lazar, Mitchell A., Tuckermann, Jan, Steger, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448680/
https://www.ncbi.nlm.nih.gov/pubmed/25957148
http://dx.doi.org/10.1101/gr.188581.114

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