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A pooling-based approach to mapping genetic variants associated with DNA methylation
DNA methylation is an epigenetic modification that plays a key role in gene regulation. Previous studies have investigated its genetic basis by mapping genetic variants that are associated with DNA methylation at specific sites, but these have been limited to microarrays that cover <2% of the gen...
Autores principales: | Kaplow, Irene M., MacIsaac, Julia L., Mah, Sarah M., McEwen, Lisa M., Kobor, Michael S., Fraser, Hunter B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448686/ https://www.ncbi.nlm.nih.gov/pubmed/25910490 http://dx.doi.org/10.1101/gr.183749.114 |
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