Deletion of a 4977-bp Fragment in the Mitochondrial Genome Is Associated with Mitochondrial Disease Severity

Large deletions in mitochondrial DNA (mtDNA) may be involved in the pathogenesis of mitochondrial disease. In this study, we investigated the relationship between a 4,977-bp deletion in the mitochondrial genome (ΔmtDNA(4977)) and the severity of clinical symptoms in patients with mitochondrial disea...

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Detalles Bibliográficos
Autores principales: Zhang, Yanchun, Ma, Yinan, Bu, Dingfang, Liu, Hui, Xia, Changyu, Zhang, Ying, Zhu, Sainan, Pan, Hong, Pei, Pei, Zheng, Xuefei, Wang, Songtao, Xu, Yufeng, Qi, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449107/
https://www.ncbi.nlm.nih.gov/pubmed/26024530
http://dx.doi.org/10.1371/journal.pone.0128624

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