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Mechanism of Testosterone Deficiency in the Transgenic Sickle Cell Mouse
Testosterone deficiency is associated with sickle cell disease (SCD), but its underlying mechanism is not known. We investigated the possible occurrence and mechanism of testosterone deficiency in a mouse model of human SCD. Transgenic sickle male mice (Sickle) exhibited decreased serum and intrates...
Autores principales: | Musicki, Biljana, Zhang, Yuxi, Chen, Haolin, Brown, Terry R., Zirkin, Barry R., Burnett, Arthur L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449127/ https://www.ncbi.nlm.nih.gov/pubmed/26023917 http://dx.doi.org/10.1371/journal.pone.0128694 |
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