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Mechanism of Testosterone Deficiency in the Transgenic Sickle Cell Mouse

Testosterone deficiency is associated with sickle cell disease (SCD), but its underlying mechanism is not known. We investigated the possible occurrence and mechanism of testosterone deficiency in a mouse model of human SCD. Transgenic sickle male mice (Sickle) exhibited decreased serum and intrates...

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Detalles Bibliográficos
Autores principales: Musicki, Biljana, Zhang, Yuxi, Chen, Haolin, Brown, Terry R., Zirkin, Barry R., Burnett, Arthur L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449127/
https://www.ncbi.nlm.nih.gov/pubmed/26023917
http://dx.doi.org/10.1371/journal.pone.0128694

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