Short-Term PTEN Inhibition Improves In Vitro Activation of Primordial Follicles, Preserves Follicular Viability, and Restores AMH Levels in Cryopreserved Ovarian Tissue From Cancer Patients

INTRODUCTION: In vitro activation and growth of primordial dormant follicles to produce fertilizable oocytes would provide a useful instrument for fertility preservation. The employment of Phosphatase and TENsin homolog (PTEN) inhibitors, in combination with Protein kinase B (Akt) stimulating molecu...

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Detalles Bibliográficos
Autores principales: Novella-Maestre, Edurne, Herraiz, Sonia, Rodríguez-Iglesias, Beatriz, Díaz-García, César, Pellicer, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449215/
https://www.ncbi.nlm.nih.gov/pubmed/26024525
http://dx.doi.org/10.1371/journal.pone.0127786

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