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TNF-α Induced by Hepatitis C Virus via TLR7 and TLR8 in Hepatocytes Supports Interferon Signaling via an Autocrine Mechanism

Invasion by infectious pathogens can elicit a range of cytokine responses from host cells. These cytokines provide the initial host defense mechanism. In this report, we demonstrate that TNF-α, a pro-inflammatory cytokine, can be induced by hepatitis C virus (HCV) in its host cells in a biphasic man...

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Detalles Bibliográficos
Autores principales:	Lee, Jiyoung, Tian, Yongjun, Chan, Stephanie Tze, Kim, Ja Yeon, Cho, Cecilia, Ou, Jing-hsiung James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449221/ https://www.ncbi.nlm.nih.gov/pubmed/26023919 http://dx.doi.org/10.1371/journal.ppat.1004937

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