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High-Fat Diet Induces Hepatic Insulin Resistance and Impairment of Synaptic Plasticity
High-fat diet (HFD)-induced obesity is associated with insulin resistance, which may affect brain synaptic plasticity through impairment of insulin-sensitive processes underlying neuronal survival, learning, and memory. The experimental model consisted of 3 month-old C57BL/6J mice fed either a norma...
Autores principales: | Liu, Zhigang, Patil, Ishan Y., Jiang, Tianyi, Sancheti, Harsh, Walsh, John P., Stiles, Bangyan L., Yin, Fei, Cadenas, Enrique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449222/ https://www.ncbi.nlm.nih.gov/pubmed/26023930 http://dx.doi.org/10.1371/journal.pone.0128274 |
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