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Interferon Regulatory Factor (IRF)-1 Is a Master Regulator of the Cross Talk between Macrophages and L929 Fibrosarcoma Cells for Nitric Oxide Dependent Tumoricidal Activity

Macrophage tumoricidal activity relies, mainly, on the release of Tumor Necrosis Factor alpha (TNFα) and/or on reactive oxygen or nitrogen intermediates. In the present work, we investigated the cytotoxic activity of resident peritoneal macrophages against L929 fibrosarcoma cell line in vitro and in...

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Detalles Bibliográficos
Autores principales:	Nascimento, Flavia R. F., Gomes, Eliane A., Russo, Momtchilo, Lepique, Ana P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449231/ https://www.ncbi.nlm.nih.gov/pubmed/25659093 http://dx.doi.org/10.1371/journal.pone.0117782

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