Increased serum IL-10 in lupus patients promotes apoptosis of T cell subsets via the caspase 8 pathway initiated by Fas signaling

We sought to investigate the expression of Fas and FasL on T cell surface and caspase 8 involvement in T cell apoptosis promoted by serum IL-10 in systemic lupus erythematosus (SLE) patients. Cells and sera were obtained from 35 SLE patients. Apoptosis of T cells in patients with SLE was increased a...

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Detalles Bibliográficos
Autores principales: Yang, Xiaofan, Sun, Bin, Wang, Huijuan, Yin, Cheng, Wang, Xiaole, Ji, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449491/
https://www.ncbi.nlm.nih.gov/pubmed/26060447
http://dx.doi.org/10.7555/JBR.29.20130037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449491/
https://www.ncbi.nlm.nih.gov/pubmed/26060447
http://dx.doi.org/10.7555/JBR.29.20130037

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