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Increased serum IL-10 in lupus patients promotes apoptosis of T cell subsets via the caspase 8 pathway initiated by Fas signaling

We sought to investigate the expression of Fas and FasL on T cell surface and caspase 8 involvement in T cell apoptosis promoted by serum IL-10 in systemic lupus erythematosus (SLE) patients. Cells and sera were obtained from 35 SLE patients. Apoptosis of T cells in patients with SLE was increased a...

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Detalles Bibliográficos
Autores principales:	Yang, Xiaofan, Sun, Bin, Wang, Huijuan, Yin, Cheng, Wang, Xiaole, Ji, Xiaohui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Editorial Department of Journal of Biomedical Research 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449491/ https://www.ncbi.nlm.nih.gov/pubmed/26060447 http://dx.doi.org/10.7555/JBR.29.20130037

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