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Optimal Pharmacologic Treatment Strategies in Obesity and Type 2 Diabetes

The prevalence of obesity has increased to pandemic levels worldwide and is related to increased risk of morbidity and mortality. Metabolic comorbidities are commonly associated with obesity and include metabolic syndrome, pre-diabetes, and type 2 diabetes. Even if the prevalence of obesity remains...

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Detalles Bibliográficos
Autores principales: Goswami, Gayotri, Shinkazh, Nataliya, Davis, Nichola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449693/
https://www.ncbi.nlm.nih.gov/pubmed/26237392
http://dx.doi.org/10.3390/jcm3020595
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author Goswami, Gayotri
Shinkazh, Nataliya
Davis, Nichola
author_facet Goswami, Gayotri
Shinkazh, Nataliya
Davis, Nichola
author_sort Goswami, Gayotri
collection PubMed
description The prevalence of obesity has increased to pandemic levels worldwide and is related to increased risk of morbidity and mortality. Metabolic comorbidities are commonly associated with obesity and include metabolic syndrome, pre-diabetes, and type 2 diabetes. Even if the prevalence of obesity remains stable until 2030, the anticipated numbers of people with diabetes will more than double as a consequence of population aging and urbanization. Weight reduction is integral in the prevention of diabetes among obese adults with pre-diabetes. Lifestyle intervention and weight reduction are also key in the management of type 2 diabetes. Weight loss is challenging for most obese patients, but for those with diabetes, it can pose an even greater challenge due to the weight gain associated with many treatment regimens. This article will review optimal treatment strategies for patients with comorbid obesity and type 2 diabetes. The role of anti-obesity agents in diabetes will also be reviewed. This literature review will provide readers with current strategies for the pharmacologic treatment of obesity and diabetes with a focus on the weight outcomes related to diabetes treatments.
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spelling pubmed-44496932015-07-28 Optimal Pharmacologic Treatment Strategies in Obesity and Type 2 Diabetes Goswami, Gayotri Shinkazh, Nataliya Davis, Nichola J Clin Med Review The prevalence of obesity has increased to pandemic levels worldwide and is related to increased risk of morbidity and mortality. Metabolic comorbidities are commonly associated with obesity and include metabolic syndrome, pre-diabetes, and type 2 diabetes. Even if the prevalence of obesity remains stable until 2030, the anticipated numbers of people with diabetes will more than double as a consequence of population aging and urbanization. Weight reduction is integral in the prevention of diabetes among obese adults with pre-diabetes. Lifestyle intervention and weight reduction are also key in the management of type 2 diabetes. Weight loss is challenging for most obese patients, but for those with diabetes, it can pose an even greater challenge due to the weight gain associated with many treatment regimens. This article will review optimal treatment strategies for patients with comorbid obesity and type 2 diabetes. The role of anti-obesity agents in diabetes will also be reviewed. This literature review will provide readers with current strategies for the pharmacologic treatment of obesity and diabetes with a focus on the weight outcomes related to diabetes treatments. MDPI 2014-06-18 /pmc/articles/PMC4449693/ /pubmed/26237392 http://dx.doi.org/10.3390/jcm3020595 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Goswami, Gayotri
Shinkazh, Nataliya
Davis, Nichola
Optimal Pharmacologic Treatment Strategies in Obesity and Type 2 Diabetes
title Optimal Pharmacologic Treatment Strategies in Obesity and Type 2 Diabetes
title_full Optimal Pharmacologic Treatment Strategies in Obesity and Type 2 Diabetes
title_fullStr Optimal Pharmacologic Treatment Strategies in Obesity and Type 2 Diabetes
title_full_unstemmed Optimal Pharmacologic Treatment Strategies in Obesity and Type 2 Diabetes
title_short Optimal Pharmacologic Treatment Strategies in Obesity and Type 2 Diabetes
title_sort optimal pharmacologic treatment strategies in obesity and type 2 diabetes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449693/
https://www.ncbi.nlm.nih.gov/pubmed/26237392
http://dx.doi.org/10.3390/jcm3020595
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