Cargando…
Optimal Pharmacologic Treatment Strategies in Obesity and Type 2 Diabetes
The prevalence of obesity has increased to pandemic levels worldwide and is related to increased risk of morbidity and mortality. Metabolic comorbidities are commonly associated with obesity and include metabolic syndrome, pre-diabetes, and type 2 diabetes. Even if the prevalence of obesity remains...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449693/ https://www.ncbi.nlm.nih.gov/pubmed/26237392 http://dx.doi.org/10.3390/jcm3020595 |
_version_ | 1782373902061666304 |
---|---|
author | Goswami, Gayotri Shinkazh, Nataliya Davis, Nichola |
author_facet | Goswami, Gayotri Shinkazh, Nataliya Davis, Nichola |
author_sort | Goswami, Gayotri |
collection | PubMed |
description | The prevalence of obesity has increased to pandemic levels worldwide and is related to increased risk of morbidity and mortality. Metabolic comorbidities are commonly associated with obesity and include metabolic syndrome, pre-diabetes, and type 2 diabetes. Even if the prevalence of obesity remains stable until 2030, the anticipated numbers of people with diabetes will more than double as a consequence of population aging and urbanization. Weight reduction is integral in the prevention of diabetes among obese adults with pre-diabetes. Lifestyle intervention and weight reduction are also key in the management of type 2 diabetes. Weight loss is challenging for most obese patients, but for those with diabetes, it can pose an even greater challenge due to the weight gain associated with many treatment regimens. This article will review optimal treatment strategies for patients with comorbid obesity and type 2 diabetes. The role of anti-obesity agents in diabetes will also be reviewed. This literature review will provide readers with current strategies for the pharmacologic treatment of obesity and diabetes with a focus on the weight outcomes related to diabetes treatments. |
format | Online Article Text |
id | pubmed-4449693 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-44496932015-07-28 Optimal Pharmacologic Treatment Strategies in Obesity and Type 2 Diabetes Goswami, Gayotri Shinkazh, Nataliya Davis, Nichola J Clin Med Review The prevalence of obesity has increased to pandemic levels worldwide and is related to increased risk of morbidity and mortality. Metabolic comorbidities are commonly associated with obesity and include metabolic syndrome, pre-diabetes, and type 2 diabetes. Even if the prevalence of obesity remains stable until 2030, the anticipated numbers of people with diabetes will more than double as a consequence of population aging and urbanization. Weight reduction is integral in the prevention of diabetes among obese adults with pre-diabetes. Lifestyle intervention and weight reduction are also key in the management of type 2 diabetes. Weight loss is challenging for most obese patients, but for those with diabetes, it can pose an even greater challenge due to the weight gain associated with many treatment regimens. This article will review optimal treatment strategies for patients with comorbid obesity and type 2 diabetes. The role of anti-obesity agents in diabetes will also be reviewed. This literature review will provide readers with current strategies for the pharmacologic treatment of obesity and diabetes with a focus on the weight outcomes related to diabetes treatments. MDPI 2014-06-18 /pmc/articles/PMC4449693/ /pubmed/26237392 http://dx.doi.org/10.3390/jcm3020595 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Review Goswami, Gayotri Shinkazh, Nataliya Davis, Nichola Optimal Pharmacologic Treatment Strategies in Obesity and Type 2 Diabetes |
title | Optimal Pharmacologic Treatment Strategies in Obesity and Type 2 Diabetes |
title_full | Optimal Pharmacologic Treatment Strategies in Obesity and Type 2 Diabetes |
title_fullStr | Optimal Pharmacologic Treatment Strategies in Obesity and Type 2 Diabetes |
title_full_unstemmed | Optimal Pharmacologic Treatment Strategies in Obesity and Type 2 Diabetes |
title_short | Optimal Pharmacologic Treatment Strategies in Obesity and Type 2 Diabetes |
title_sort | optimal pharmacologic treatment strategies in obesity and type 2 diabetes |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449693/ https://www.ncbi.nlm.nih.gov/pubmed/26237392 http://dx.doi.org/10.3390/jcm3020595 |
work_keys_str_mv | AT goswamigayotri optimalpharmacologictreatmentstrategiesinobesityandtype2diabetes AT shinkazhnataliya optimalpharmacologictreatmentstrategiesinobesityandtype2diabetes AT davisnichola optimalpharmacologictreatmentstrategiesinobesityandtype2diabetes |