Glycogen synthase kinase-3β promotes cyst expansion in polycystic kidney disease

Polycystic kidney diseases (PKDs) are inherited disorders characterized by the formation of fluid filled renal cysts. Elevated cAMP levels in PKDs stimulate progressive cyst enlargement involving cell proliferation and transepithelial fluid secretion often leading to end stage renal disease. The gly...

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Detalles Bibliográficos
Autores principales: Tao, Shixin, Kakade, Vijayakumar, Woodgett, James, Pandey, Pankaj, Suderman, Erin, Rajagopal, Madhumitha, Rao, Reena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449797/
https://www.ncbi.nlm.nih.gov/pubmed/25629553
http://dx.doi.org/10.1038/ki.2014.427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449797/
https://www.ncbi.nlm.nih.gov/pubmed/25629553
http://dx.doi.org/10.1038/ki.2014.427

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