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Glycogen synthase kinase-3β promotes cyst expansion in polycystic kidney disease
Polycystic kidney diseases (PKDs) are inherited disorders characterized by the formation of fluid filled renal cysts. Elevated cAMP levels in PKDs stimulate progressive cyst enlargement involving cell proliferation and transepithelial fluid secretion often leading to end stage renal disease. The gly...
Autores principales: | Tao, Shixin, Kakade, Vijayakumar, Woodgett, James, Pandey, Pankaj, Suderman, Erin, Rajagopal, Madhumitha, Rao, Reena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449797/ https://www.ncbi.nlm.nih.gov/pubmed/25629553 http://dx.doi.org/10.1038/ki.2014.427 |
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