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TCEB1-mutated Renal Cell Carcinoma: A Distinct Genomic and Morphologic Subtype

Integrated sequencing analysis identified a group of tumors among clear cell renal cell carcinomas characterized by hotspot mutations in TCEB1 (a gene that contributes to the VHL complex to ubiquitinate hypoxia inducible factor). We analyzed 11 tumors from two distinct cohorts with TCEB1 mutations a...

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Detalles Bibliográficos
Autores principales:	Hakimi, A Ari, Tickoo, Satish K, Jacobsen, Anders, Sarungbam, Judy, Sfakianos, John P, Sato, Yusuke, Morikawa, Teppei, Kume, Haruki, Fukayama, Masashi, Homma, Yukio, Chen, Ying-Bei, Sankin, Alexander, Mano, Roy, Coleman, Jonathan A, Russo, Paul, Ogawa, Seishi, Sander, Chris, Hsieh, James J, Reuter, Victor E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449825/ https://www.ncbi.nlm.nih.gov/pubmed/25676555 http://dx.doi.org/10.1038/modpathol.2015.6

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