Semaphorin4A Is Cytotoxic to Oligodendrocytes and Is Elevated in Microglia and Multiple Sclerosis

We have previously established that T cell immunoglobulin and mucin domain containing 2 (Tim2) is an H-ferritin receptor on oligodendrocytes (OLs). Tim2 also binds Semaphorin4A (Sema4A). Sema4A is expressed by lymphocytes, and its role in immune activation is known; however, its relationship to dise...

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Detalles Bibliográficos
Autores principales: Leitner, Dominique F., Todorich, Bozho, Zhang, Xuesheng, Connor, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449839/
https://www.ncbi.nlm.nih.gov/pubmed/26024919
http://dx.doi.org/10.1177/1759091415587502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449839/
https://www.ncbi.nlm.nih.gov/pubmed/26024919
http://dx.doi.org/10.1177/1759091415587502

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