Cargando…

Natural Products for Antithrombosis

Thrombosis is considered to be closely related to several diseases such as atherosclerosis, ischemic heart disease and stroke, as well as rheumatoid arthritis, hyperuricemia, and various inflammatory conditions. More and more studies have been focused on understanding the mechanism of molecular and...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Cen, Yang, Feng-Qing, Zhang, Qian, Wang, Feng-Qin, Hu, Yuan-Jia, Xia, Zhi-Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449941/
https://www.ncbi.nlm.nih.gov/pubmed/26075003
http://dx.doi.org/10.1155/2015/876426
_version_ 1782373934660845568
author Chen, Cen
Yang, Feng-Qing
Zhang, Qian
Wang, Feng-Qin
Hu, Yuan-Jia
Xia, Zhi-Ning
author_facet Chen, Cen
Yang, Feng-Qing
Zhang, Qian
Wang, Feng-Qin
Hu, Yuan-Jia
Xia, Zhi-Ning
author_sort Chen, Cen
collection PubMed
description Thrombosis is considered to be closely related to several diseases such as atherosclerosis, ischemic heart disease and stroke, as well as rheumatoid arthritis, hyperuricemia, and various inflammatory conditions. More and more studies have been focused on understanding the mechanism of molecular and cellular basis of thrombus formation as well as preventing thrombosis for the treatment of thrombotic diseases. In reality, there is considerable interest in the role of natural products and their bioactive components in the prevention and treatment of thrombosis related disorders. This paper briefly describes the mechanisms of thrombus formation on three aspects, including coagulation system, platelet activation, and aggregation, and change of blood flow conditions. Furthermore, the natural products for antithrombosis by anticoagulation, antiplatelet aggregation, and fibrinolysis were summarized, respectively.
format Online
Article
Text
id pubmed-4449941
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-44499412015-06-14 Natural Products for Antithrombosis Chen, Cen Yang, Feng-Qing Zhang, Qian Wang, Feng-Qin Hu, Yuan-Jia Xia, Zhi-Ning Evid Based Complement Alternat Med Review Article Thrombosis is considered to be closely related to several diseases such as atherosclerosis, ischemic heart disease and stroke, as well as rheumatoid arthritis, hyperuricemia, and various inflammatory conditions. More and more studies have been focused on understanding the mechanism of molecular and cellular basis of thrombus formation as well as preventing thrombosis for the treatment of thrombotic diseases. In reality, there is considerable interest in the role of natural products and their bioactive components in the prevention and treatment of thrombosis related disorders. This paper briefly describes the mechanisms of thrombus formation on three aspects, including coagulation system, platelet activation, and aggregation, and change of blood flow conditions. Furthermore, the natural products for antithrombosis by anticoagulation, antiplatelet aggregation, and fibrinolysis were summarized, respectively. Hindawi Publishing Corporation 2015 2015-05-17 /pmc/articles/PMC4449941/ /pubmed/26075003 http://dx.doi.org/10.1155/2015/876426 Text en Copyright © 2015 Cen Chen et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Chen, Cen
Yang, Feng-Qing
Zhang, Qian
Wang, Feng-Qin
Hu, Yuan-Jia
Xia, Zhi-Ning
Natural Products for Antithrombosis
title Natural Products for Antithrombosis
title_full Natural Products for Antithrombosis
title_fullStr Natural Products for Antithrombosis
title_full_unstemmed Natural Products for Antithrombosis
title_short Natural Products for Antithrombosis
title_sort natural products for antithrombosis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449941/
https://www.ncbi.nlm.nih.gov/pubmed/26075003
http://dx.doi.org/10.1155/2015/876426
work_keys_str_mv AT chencen naturalproductsforantithrombosis
AT yangfengqing naturalproductsforantithrombosis
AT zhangqian naturalproductsforantithrombosis
AT wangfengqin naturalproductsforantithrombosis
AT huyuanjia naturalproductsforantithrombosis
AT xiazhining naturalproductsforantithrombosis