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In Vivo Approaches Reveal a Key Role for DCs in CD4+ T Cell Activation and Parasite Clearance during the Acute Phase of Experimental Blood-Stage Malaria

Dendritic cells (DCs) are phagocytes that are highly specialized for antigen presentation. Heterogeneous populations of macrophages and DCs form a phagocyte network inside the red pulp (RP) of the spleen, which is a major site for the control of blood-borne infections such as malaria. However, the d...

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Detalles Bibliográficos
Autores principales: Borges da Silva, Henrique, Fonseca, Raíssa, Cassado, Alexandra dos Anjos, Machado de Salles, Érika, de Menezes, Maria Nogueira, Langhorne, Jean, Perez, Katia Regina, Cuccovia, Iolanda Midea, Ryffel, Bernhard, Barreto, Vasco M., Marinho, Cláudio Romero Farias, Boscardin, Silvia Beatriz, Álvarez, José Maria, D’Império-Lima, Maria Regina, Tadokoro, Carlos Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450059/
https://www.ncbi.nlm.nih.gov/pubmed/25658925
http://dx.doi.org/10.1371/journal.ppat.1004598