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In Vivo Approaches Reveal a Key Role for DCs in CD4+ T Cell Activation and Parasite Clearance during the Acute Phase of Experimental Blood-Stage Malaria
Dendritic cells (DCs) are phagocytes that are highly specialized for antigen presentation. Heterogeneous populations of macrophages and DCs form a phagocyte network inside the red pulp (RP) of the spleen, which is a major site for the control of blood-borne infections such as malaria. However, the d...
Autores principales: | Borges da Silva, Henrique, Fonseca, Raíssa, Cassado, Alexandra dos Anjos, Machado de Salles, Érika, de Menezes, Maria Nogueira, Langhorne, Jean, Perez, Katia Regina, Cuccovia, Iolanda Midea, Ryffel, Bernhard, Barreto, Vasco M., Marinho, Cláudio Romero Farias, Boscardin, Silvia Beatriz, Álvarez, José Maria, D’Império-Lima, Maria Regina, Tadokoro, Carlos Eduardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450059/ https://www.ncbi.nlm.nih.gov/pubmed/25658925 http://dx.doi.org/10.1371/journal.ppat.1004598 |
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