Development of an IP-Free Biotechnology Platform for Constitutive Production of HPV16 L1 Capsid Protein Using the Pichia pastoris PGK1 Promoter

The human papillomavirus (HPV) L1 major capsid protein, which forms the basis of the currently available vaccines against cervical cancer, self-assembles into virus-like particles (VLPs) when expressed heterologously. We report the development of a biotechnology platform for HPV16 L1 protein express...

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Detalles Bibliográficos
Autores principales: Mariz, F. C., Coimbra, E. C., Jesus, A. L. S., Nascimento, L. M., Torres, F. A. G., Freitas, A. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450287/
https://www.ncbi.nlm.nih.gov/pubmed/26090426
http://dx.doi.org/10.1155/2015/594120

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