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Local chromatin environment of a Polycomb target gene instructs its own epigenetic inheritance

Inheritance of gene expression states is fundamental for cells to ‘remember’ past events, such as environmental or developmental cues. The conserved Polycomb Repressive Complex 2 (PRC2) maintains epigenetic repression of many genes in animals and plants and modifies chromatin at its targets. Histone...

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Detalles Bibliográficos
Autores principales: Berry, Scott, Hartley, Matthew, Olsson, Tjelvar S G, Dean, Caroline, Howard, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450441/
https://www.ncbi.nlm.nih.gov/pubmed/25955967
http://dx.doi.org/10.7554/eLife.07205