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The role of PPAR activation during the systemic response to brain injury

BACKGROUND: Fenofibrate, a PPAR-α activator, has shown promising results as a neuroprotective therapy, with proposed anti-inflammatory and anti-oxidant effects. However, it displays poor blood-brain barrier permeability leading to some ambiguity over its mechanism of action. Experimentally induced b...

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Detalles Bibliográficos
Autores principales:	Losey, Patrick, Ladds, Emma, Laprais, Maud, Geuvel, Borna, Burns, Laura, Bordet, Regis, Anthony, Daniel C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450490/ https://www.ncbi.nlm.nih.gov/pubmed/25994490 http://dx.doi.org/10.1186/s12974-015-0295-7

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