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Receptor tyrosine kinases modulate distinct transcriptional programs by differential usage of intracellular pathways

Receptor tyrosine kinases (RTKs) signal through shared intracellular pathways yet mediate distinct outcomes across many cell types. To investigate the mechanisms underlying RTK specificity in craniofacial development, we performed RNA-seq to delineate the transcriptional response to platelet-derived...

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Detalles Bibliográficos
Autores principales:	Vasudevan, Harish N, Mazot, Pierre, He, Fenglei, Soriano, Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Computational and Systems Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450512/ https://www.ncbi.nlm.nih.gov/pubmed/25951516 http://dx.doi.org/10.7554/eLife.07186

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