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Does Corneal Hysteresis Correlate with Endothelial Cell Density?
BACKGROUND: Our aim was to determine if there is a correlation between corneal biomechanical properties, endothelial cell count, and corneal pachymetry in healthy corneas. MATERIAL/METHODS: Ninety-two eyes of all subjects underwent complete ocular examination, including intraocular pressure measurem...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450604/ https://www.ncbi.nlm.nih.gov/pubmed/25994302 http://dx.doi.org/10.12659/MSM.893589 |
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author | Akova-Budak, Berna Kıvanç, Sertaç Argun |
author_facet | Akova-Budak, Berna Kıvanç, Sertaç Argun |
author_sort | Akova-Budak, Berna |
collection | PubMed |
description | BACKGROUND: Our aim was to determine if there is a correlation between corneal biomechanical properties, endothelial cell count, and corneal pachymetry in healthy corneas. MATERIAL/METHODS: Ninety-two eyes of all subjects underwent complete ocular examination, including intraocular pressure measurement by Goldmann applanation tonometer, objective refraction, and slit-lamp biomicroscopy. Topographic measurements and corneal pachymetry were performed using a Scheimpflug-based (Pentacam, Oculus, Germany) corneal topographer. Corneal hysteresis (CH) and corneal resistance factor (CRF) were measured with an Ocular Response Analyzer (ORA, Reichert Ophthalmic Instruments, Buffalo, NY). Endothelial cell count measurement was done using a specular microscope (CellChek, Konan, USA). RESULTS: Right eye values of the subjects were taken for the study. The mean CH was 11.5±1.7 mmHg and the mean CRF was 11.2±1.4 mmHg. Mean intraocular pressure was 15.3±2.3 mmHg. The mean endothelial cell count was 2754±205 cells/mm(2). No correlation was found between biomechanical properties of cornea and endothelial cell count. There was a significant positive correlation between CH, CRF, and corneal thickness (p<0.001; r=0.79). CONCLUSIONS: The corneal biomechanical properties significantly correlated with corneal thickness. We found no correlation between CH and CRF with the endothelial cell density in normal subjects. |
format | Online Article Text |
id | pubmed-4450604 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | International Scientific Literature, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-44506042015-06-16 Does Corneal Hysteresis Correlate with Endothelial Cell Density? Akova-Budak, Berna Kıvanç, Sertaç Argun Med Sci Monit Clinical Research BACKGROUND: Our aim was to determine if there is a correlation between corneal biomechanical properties, endothelial cell count, and corneal pachymetry in healthy corneas. MATERIAL/METHODS: Ninety-two eyes of all subjects underwent complete ocular examination, including intraocular pressure measurement by Goldmann applanation tonometer, objective refraction, and slit-lamp biomicroscopy. Topographic measurements and corneal pachymetry were performed using a Scheimpflug-based (Pentacam, Oculus, Germany) corneal topographer. Corneal hysteresis (CH) and corneal resistance factor (CRF) were measured with an Ocular Response Analyzer (ORA, Reichert Ophthalmic Instruments, Buffalo, NY). Endothelial cell count measurement was done using a specular microscope (CellChek, Konan, USA). RESULTS: Right eye values of the subjects were taken for the study. The mean CH was 11.5±1.7 mmHg and the mean CRF was 11.2±1.4 mmHg. Mean intraocular pressure was 15.3±2.3 mmHg. The mean endothelial cell count was 2754±205 cells/mm(2). No correlation was found between biomechanical properties of cornea and endothelial cell count. There was a significant positive correlation between CH, CRF, and corneal thickness (p<0.001; r=0.79). CONCLUSIONS: The corneal biomechanical properties significantly correlated with corneal thickness. We found no correlation between CH and CRF with the endothelial cell density in normal subjects. International Scientific Literature, Inc. 2015-05-21 /pmc/articles/PMC4450604/ /pubmed/25994302 http://dx.doi.org/10.12659/MSM.893589 Text en © Med Sci Monit, 2015 This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License |
spellingShingle | Clinical Research Akova-Budak, Berna Kıvanç, Sertaç Argun Does Corneal Hysteresis Correlate with Endothelial Cell Density? |
title | Does Corneal Hysteresis Correlate with Endothelial Cell Density? |
title_full | Does Corneal Hysteresis Correlate with Endothelial Cell Density? |
title_fullStr | Does Corneal Hysteresis Correlate with Endothelial Cell Density? |
title_full_unstemmed | Does Corneal Hysteresis Correlate with Endothelial Cell Density? |
title_short | Does Corneal Hysteresis Correlate with Endothelial Cell Density? |
title_sort | does corneal hysteresis correlate with endothelial cell density? |
topic | Clinical Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450604/ https://www.ncbi.nlm.nih.gov/pubmed/25994302 http://dx.doi.org/10.12659/MSM.893589 |
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