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Long-term mortality among older adults with burn injury: a population-based study in Australia

OBJECTIVE: To assess if burn injury in older adults is associated with changes in long-term all-cause mortality and to estimate the increased risk of death attributable to burn injury. METHODS: We conducted a population-based matched longitudinal study – based on administrative data from Western Aus...

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Autores principales: Duke, Janine M, Boyd, James H, Rea, Suzanne, Randall, Sean M, Wood, Fiona M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: World Health Organization 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450710/
https://www.ncbi.nlm.nih.gov/pubmed/26240461
http://dx.doi.org/10.2471/BLT.14.149146
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author Duke, Janine M
Boyd, James H
Rea, Suzanne
Randall, Sean M
Wood, Fiona M
author_facet Duke, Janine M
Boyd, James H
Rea, Suzanne
Randall, Sean M
Wood, Fiona M
author_sort Duke, Janine M
collection PubMed
description OBJECTIVE: To assess if burn injury in older adults is associated with changes in long-term all-cause mortality and to estimate the increased risk of death attributable to burn injury. METHODS: We conducted a population-based matched longitudinal study – based on administrative data from Western Australia’s hospital morbidity data system and death register. A cohort of 6014 individuals who were aged at least 45 years when hospitalized for a first burn injury in 1980–2012 was identified. A non-injury comparison cohort, randomly selected from Western Australia’s electoral roll (n = 25 759), was matched to the patients. We used Kaplan–Meier plots and Cox proportional hazards regression to analyse the data and generated mortality rate ratios and attributable risk percentages. FINDINGS: For those hospitalized with burns, 180 (3%) died in hospital and 2498 (42%) died after discharge. Individuals with burn injury had a 1.4-fold greater mortality rate than those with no injury (95% confidence interval, CI: 1.3–1.5). In this cohort, the long-term mortality attributable to burn injury was 29%. Mortality risk was increased by both severe and minor burns, with adjusted mortality rate ratios of 1.3 (95% CI: 1.1–1.9) and 2.1 (95% CI: 1.9–2.3), respectively. CONCLUSION: Burn injury is associated with increased long-term mortality. In our study population, sole reliance on data on in-hospital deaths would lead to an underestimate of the true mortality burden associated with burn injury.
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spelling pubmed-44507102015-08-03 Long-term mortality among older adults with burn injury: a population-based study in Australia Duke, Janine M Boyd, James H Rea, Suzanne Randall, Sean M Wood, Fiona M Bull World Health Organ Research OBJECTIVE: To assess if burn injury in older adults is associated with changes in long-term all-cause mortality and to estimate the increased risk of death attributable to burn injury. METHODS: We conducted a population-based matched longitudinal study – based on administrative data from Western Australia’s hospital morbidity data system and death register. A cohort of 6014 individuals who were aged at least 45 years when hospitalized for a first burn injury in 1980–2012 was identified. A non-injury comparison cohort, randomly selected from Western Australia’s electoral roll (n = 25 759), was matched to the patients. We used Kaplan–Meier plots and Cox proportional hazards regression to analyse the data and generated mortality rate ratios and attributable risk percentages. FINDINGS: For those hospitalized with burns, 180 (3%) died in hospital and 2498 (42%) died after discharge. Individuals with burn injury had a 1.4-fold greater mortality rate than those with no injury (95% confidence interval, CI: 1.3–1.5). In this cohort, the long-term mortality attributable to burn injury was 29%. Mortality risk was increased by both severe and minor burns, with adjusted mortality rate ratios of 1.3 (95% CI: 1.1–1.9) and 2.1 (95% CI: 1.9–2.3), respectively. CONCLUSION: Burn injury is associated with increased long-term mortality. In our study population, sole reliance on data on in-hospital deaths would lead to an underestimate of the true mortality burden associated with burn injury. World Health Organization 2015-06-01 2015-04-20 /pmc/articles/PMC4450710/ /pubmed/26240461 http://dx.doi.org/10.2471/BLT.14.149146 Text en (c) 2015 The authors; licensee World Health Organization. This is an open access article distributed under the terms of the Creative Commons Attribution IGO License (http://creativecommons.org/licenses/by/3.0/igo/legalcode), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In any reproduction of this article there should not be any suggestion that WHO or this article endorse any specific organization or products. The use of the WHO logo is not permitted. This notice should be preserved along with the article's original URL.
spellingShingle Research
Duke, Janine M
Boyd, James H
Rea, Suzanne
Randall, Sean M
Wood, Fiona M
Long-term mortality among older adults with burn injury: a population-based study in Australia
title Long-term mortality among older adults with burn injury: a population-based study in Australia
title_full Long-term mortality among older adults with burn injury: a population-based study in Australia
title_fullStr Long-term mortality among older adults with burn injury: a population-based study in Australia
title_full_unstemmed Long-term mortality among older adults with burn injury: a population-based study in Australia
title_short Long-term mortality among older adults with burn injury: a population-based study in Australia
title_sort long-term mortality among older adults with burn injury: a population-based study in australia
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450710/
https://www.ncbi.nlm.nih.gov/pubmed/26240461
http://dx.doi.org/10.2471/BLT.14.149146
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