Cargando…

Active immunization with Tocilizumab mimotopes induces specific immune responses

BACKGROUND: Tocilizumab is a humanized monoclonal antibody showing high-affinity binding to both soluble interleukin-6 receptor (sIL-6R) and membrane bound IL-6R (mIL-6R), thereby preventing pro-inflammatory effects of IL-6. However, therapeutic antibodies still have practical limitations. To overco...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Lin, Xing, Rui, Li, Changhong, Liu, Yuan, Sun, Lin, Liu, Xiangyuan, Wang, Yongfu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450830/ https://www.ncbi.nlm.nih.gov/pubmed/26033236 http://dx.doi.org/10.1186/s12896-015-0161-9

Ejemplares similares

Identification of anti-CD98 antibody mimotopes for inducing antibodies with antitumor activity by mimotope immunization
por: Saito, Misa, et al.
Publicado: (2014)

Induction of anti-EGFR immune response with mimotopes identified from a phage display peptide library by panitumumab
por: Wang, Aidong, et al.
Publicado: (2016)

Characterizing Complex Polysera Produced by Antigen-Specific Immunization through the Use of Affinity-Selected Mimotopes
por: Denisova, Galina, et al.
Publicado: (2009)

A New Strategy Toward B Cell-Based Cancer Vaccines by Active Immunization With Mimotopes of Immune Checkpoint Inhibitors
por: Tobias, Joshua, et al.
Publicado: (2020)

Induction of aquaporin 4-reactive antibodies in Lewis rats immunized with aquaporin 4 mimotopes
por: Tsymala, Irina, et al.
Publicado: (2020)

Mimotope vaccination for epitope-specific induction of anti-VEGF antibodies
por: Li, Weina, et al.
Publicado: (2013)

Identification of Peptide Mimotope Ligands for Natalizumab
por: Ruff, Laura E., et al.
Publicado: (2018)

Identification of cancer-specific motifs in mimotope profiles of serum antibody repertoire
por: Gerasimov, Ekaterina, et al.
Publicado: (2017)

MimoDB 2.0: a mimotope database and beyond
por: Huang, Jian, et al.
Publicado: (2012)

Identification of Functional mimotopes of human Vasorin Ectodomain by Biopanning
por: Li, Da, et al.
Publicado: (2018)

The Relationship Between B-Cell Epitope and Mimotope Sequences
por: Zhang, Chunhua, et al.
Publicado: (2016)

Mimotopes selected with neutralizing antibodies against multiple subtypes of influenza A
por: Zhong, Yanwei, et al.
Publicado: (2011)

Proof of concept study with an HER-2 mimotope anticancer vaccine deduced from a novel AAV-mimotope library platform
por: Singer, Josef, et al.
Publicado: (2016)

Interleukin-21 promotes osteoclastogenesis in RAW264.7 cells through the PI3K/AKT signaling pathway independently of RANKL
por: Xing, Rui, et al.
Publicado: (2016)

A vaccine with Aβ oligomer-specific mimotope attenuates cognitive deficits and brain pathologies in transgenic mice with Alzheimer’s disease
por: Wang, Shao-wei, et al.
Publicado: (2017)

K-Ras Peptide Mimotope Induces Antigen Specific Th1 and B-Cell Immune Responses against G12A-Mutated K-Ras Antigen in Balb/c Mice
por: Siak, Pui Yan, et al.
Publicado: (2021)

Identification of a mimotope of an infectious bronchitis virus S1 protein
por: Zhou, Jingming, et al.
Publicado: (2021)

An apolipoprotein B100 mimotope prevents obesity in mice
por: Kim, Hyo Joon, et al.
Publicado: (2015)

Identification of mimotopes of Mycobacterium leprae as potential diagnostic reagents
por: Alban, Silvana M, et al.
Publicado: (2013)

Specificity of Mimotope-Induced Anti-High Molecular Weight-Melanoma Associated Antigen (HMW-MAA) Antibodies Does Not Ensure Biological Activity
por: Latzka, Julia, et al.
Publicado: (2011)

Specific Antibodies Reacting with SV40 Large T Antigen Mimotopes in Serum Samples of Healthy Subjects
por: Tognon, Mauro, et al.
Publicado: (2016)

Identification of Highly Cross-Reactive Mimotopes for a Public T Cell Response in Murine Melanoma
por: Grace, Beth E., et al.
Publicado: (2022)

Conformational B-Cell Epitope Prediction Method Based on Antigen Preprocessing and Mimotopes Analysis
por: Sun, Pingping, et al.
Publicado: (2015)

Peptide mimotopes of malondialdehyde epitopes for clinical applications in cardiovascular disease
por: Amir, Shahzada, et al.
Publicado: (2012)

Tocilizumab Induces IL-10-Mediated Immune Tolerance in Invasive Candidiasis
por: Tan, Zhaohong, et al.
Publicado: (2021)

Improvement of Treg immune response after treatment with tocilizumab in giant cell arteritis
por: Samson, Maxime, et al.
Publicado: (2021)

Mimotopes for Alloreactive and Conventional T Cells in a Peptide–MHC Display Library
por: Crawford, Frances, et al.
Publicado: (2004)

Identification of Peptide Mimotopes of Trypanosoma brucei gambiense Variant Surface Glycoproteins
por: Van Nieuwenhove, Liesbeth Carolien, et al.
Publicado: (2011)

P19-15. Synthesis of multivalent mimotopes as potential vaccine candidates
por: Go, JG, et al.
Publicado: (2009)

A baculovirus-conjugated mimotope vaccine targeting Mycobacterium tuberculosis lipoarabinomannan
por: Shin, Hyun-Jin, et al.
Publicado: (2017)

A nanobody-derived mimotope against VEGF inhibits cancer angiogenesis
por: Karami, Elmira, et al.
Publicado: (2020)

A Case Report of Immune Checkpoint Inhibitor-Induced Aortitis Treated with Tocilizumab
por: Bloomer, Chance H., et al.
Publicado: (2022)

Mimotopes for Mycotoxins Diagnosis Based on Random Peptides or Recombinant Antibodies from Phage Library
por: Sun, Wei, et al.
Publicado: (2021)

MimoDB: a New Repository for Mimotope Data Derived from Phage Display Technology
por: Ru, Beibei, et al.
Publicado: (2010)

Induction of colitis in mice with food allergen-specific immune response
por: Li, Lin-Jing, et al.
Publicado: (2016)

Development and comparative study of chemosynthesized antigen and mimotope-based immunoassays for class-specific analysis of O,O-dimethyl organophosphorus pesticides
por: Zhao, Fengchun, et al.
Publicado: (2016)

Mimotope vaccine efficacy gets a "boost" from native tumor antigens
por: Buhrman, Jonathan D., et al.
Publicado: (2013)

Development of a Mimotope Vaccine Targeting the Staphylococcus aureus Quorum Sensing Pathway
por: O’Rourke, John P., et al.
Publicado: (2014)

Selection of a Mimotope Peptide of S-adenosyl-l-homocysteine and Its Application in Immunoassays
por: Wu, Chun, et al.
Publicado: (2013)

Phage Display Detection of Mimotopes that Are Shared Epitopes of Clinically and Epidemiologically Relevant Enterobacteria
por: Navarro, Armando, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_tum1na0392jeiqkat89irofmgd