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Cancer Cells Hijack PRC2 to Modify Multiple Cytokine Pathways

Polycomb Repressive Complex 2 (PRC2) is an epigenetic regulator induced in many cancers. It is thought to drive tumorigenesis by repressing division, stemness, and/or developmental regulators. Cancers evade immune detection, and diverse immune regulators are perturbed in different tumors. It is uncl...

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Detalles Bibliográficos
Autores principales: Abou El Hassan, Mohamed, Huang, Katherine, Eswara, Manoja B. K., Zhao, Michael, Song, Lan, Yu, Tao, Liu, Yu, Liu, Jeffrey C., McCurdy, Sean, Ma, Anqi, Wither, Joan, Jin, Jian, Zacksenhaus, Eldad, Wrana, Jeffrey L., Bremner, Rod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450877/
https://www.ncbi.nlm.nih.gov/pubmed/26030458
http://dx.doi.org/10.1371/journal.pone.0126466