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Cancer Cells Hijack PRC2 to Modify Multiple Cytokine Pathways
Polycomb Repressive Complex 2 (PRC2) is an epigenetic regulator induced in many cancers. It is thought to drive tumorigenesis by repressing division, stemness, and/or developmental regulators. Cancers evade immune detection, and diverse immune regulators are perturbed in different tumors. It is uncl...
Autores principales: | Abou El Hassan, Mohamed, Huang, Katherine, Eswara, Manoja B. K., Zhao, Michael, Song, Lan, Yu, Tao, Liu, Yu, Liu, Jeffrey C., McCurdy, Sean, Ma, Anqi, Wither, Joan, Jin, Jian, Zacksenhaus, Eldad, Wrana, Jeffrey L., Bremner, Rod |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450877/ https://www.ncbi.nlm.nih.gov/pubmed/26030458 http://dx.doi.org/10.1371/journal.pone.0126466 |
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