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Caveolar disruption causes contraction of rat femoral arteries via reduced basal NO release and subsequent closure of BK(Ca) channels

Background and Purpose. Caveolae act as signalling hubs in endothelial and smooth muscle cells. Caveolar disruption by the membrane cholesterol depleting agent methyl-β-cyclodextrin (M-β-CD) has various functional effects on arteries including (i) impairment of endothelium-dependent relaxation, and...

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Detalles Bibliográficos
Autores principales:	Al-Brakati, AY, Kamishima, T, Dart, C, Quayle, JM
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2015
Materias:	Anatomy and Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451037/ https://www.ncbi.nlm.nih.gov/pubmed/26038721 http://dx.doi.org/10.7717/peerj.966

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