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DYRK1A controls the transition from proliferation to quiescence during lymphoid development by destabilizing Cyclin D3
Pre–B and pre–T lymphocytes must orchestrate a transition from a highly proliferative state to a quiescent one during development. Cyclin D3 is essential for these cells’ proliferation, but little is known about its posttranslational regulation at this stage. Here, we show that the dual specificity...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451127/ https://www.ncbi.nlm.nih.gov/pubmed/26008897 http://dx.doi.org/10.1084/jem.20150002 |