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BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival

B cell activating factor (BAFF) stimulation of the BAFF receptor (BAFF-R) is essential for the homeostatic survival of mature B cells. Earlier in vitro experiments with inhibitors that block MEK 1 and 2 suggested that activation of ERK 1 and 2 MAP kinases is required for BAFF-R to promote B cell sur...

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Detalles Bibliográficos
Autores principales:	Jacque, Emilie, Schweighoffer, Edina, Tybulewicz, Victor L.J., Ley, Steven C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451135/ https://www.ncbi.nlm.nih.gov/pubmed/25987726 http://dx.doi.org/10.1084/jem.20142127

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