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Detecting functional changes with [(18)F]FAZA in a renal cell carcinoma mouse model following sunitinib therapy
BACKGROUND: The multitargeting tyrosine kinase inhibitor (TKI) sunitinib is currently the first-line drug therapy for metastasizing renal cell carcinoma (RCC). TKIs have profound effects on tumor angiogenesis, leading to modifications of the tumor microenvironment. The goal of this study was to dete...
Autores principales: | Chapman, David W, Jans, Hans-Sonke, Ma, Ivy, Mercer, John R, Wiebe, Leonard I, Wuest, Melinda, Moore, Ronald B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451188/ https://www.ncbi.nlm.nih.gov/pubmed/26116107 http://dx.doi.org/10.1186/s13550-014-0027-5 |
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