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Polycomb-Dependent Repression of the Potassium Channel-Encoding Gene KCNA5 Promotes Cancer Cell Survival Under Conditions of Stress

Relapse after clinical remission remains a leading cause of cancer-associated death. Although the mechanisms of tumor relapse are complex, the ability of cancer cells to survive physiologic stress is a prerequisite for recurrence. Ewing sarcoma (ES) and neuroblastoma (NB) are aggressive cancers that...

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Detalles Bibliográficos
Autores principales: Ryland, Katherine E, Svoboda, Laurie K., Vesely, Eileen D, McIntyre, Jeremy C., Zhang, Lian, Martens, Jeffrey R., Lawlor, Elizabeth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451446/
https://www.ncbi.nlm.nih.gov/pubmed/25435365
http://dx.doi.org/10.1038/onc.2014.384