Mortalin (GRP75/HSPA9) upregulation promotes survival and proliferation of medullary thyroid carcinoma cells

Medullary thyroid carcinoma (MTC) is a neuroendocrine tumor mainly caused by mutations in the RET proto-oncogene. For therapy of advanced MTC, the Food and Drug Administration recently approved vandetanib and cabozantinib, the tyrosine kinase inhibitors targeting RET, vascular endothelial growth fac...

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Detalles Bibliográficos
Autores principales: Starenki, Dmytro, Hong, Seung-Keun, Lloyd, Ricardo V., Park, Jong-In
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451452/
https://www.ncbi.nlm.nih.gov/pubmed/25435367
http://dx.doi.org/10.1038/onc.2014.392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451452/
https://www.ncbi.nlm.nih.gov/pubmed/25435367
http://dx.doi.org/10.1038/onc.2014.392

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