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A Possible Role for WNT5A Hypermethylation in Pediatric Acute Lymphoblastic Leukemia

OBJECTIVE: WNT5A is one of the most studied noncanonical WNT ligands and is shown to be deregulated in different tumor types. Our aim was to clarify whether hypermethylation might be the cause of low WNT5A mRNA levels and whether we could restore this downregulation by reversing the event. MATERIALS...

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Detalles Bibliográficos
Autores principales:	Hatırnaz Ng, Özden, Fırtına, Sinem, Can, İsmail, Karakaş, Zeynep, Ağaoğlu, Leyla, Doğru, Ömer, Celkan, Tiraje, Akçay, Arzu, Yıldırmak, Yıldız, Timur, Çetin, Özbek, Uğur, Sayitoğlu, Müge
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Galenos Publishing 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451480/ https://www.ncbi.nlm.nih.gov/pubmed/26316480 http://dx.doi.org/10.4274/tjh.2013.0296

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