Associations of Haplotypes Upstream of IRS1 with Insulin Resistance, Type 2 Diabetes, Dyslipidemia, Preclinical Atherosclerosis, and Skeletal Muscle LOC646736 mRNA Levels

The genomic region ~500 kb upstream of IRS1 has been implicated in insulin resistance, type 2 diabetes, adverse lipid profile, and cardiovascular risk. To gain further insight into this chromosomal region, we typed four SNPs in a cross-sectional cohort and subjects with type 2 diabetes recruited fro...

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Detalles Bibliográficos
Autores principales: Soyal, Selma M., Felder, Thomas, Auer, Simon, Oberkofler, Hannes, Iglseder, Bernhard, Paulweber, Bernhard, Dossena, Silvia, Nofziger, Charity, Paulmichl, Markus, Esterbauer, Harald, Krempler, Franz, Patsch, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451528/
https://www.ncbi.nlm.nih.gov/pubmed/26090471
http://dx.doi.org/10.1155/2015/405371

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