Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses

We summarized the most recent findings on the role of autophagy in antiviral immune response. We described how viruses have developed strategies to subvert the autophagic process. A particular attention has been given to Epstein-Barr and Kaposi's sarcoma associated Herpesvirus, viruses studied...

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Detalles Bibliográficos
Autores principales: Santarelli, Roberta, Granato, Marisa, Faggioni, Alberto, Cirone, Mara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451563/
https://www.ncbi.nlm.nih.gov/pubmed/26090494
http://dx.doi.org/10.1155/2015/546063
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author Santarelli, Roberta
Granato, Marisa
Faggioni, Alberto
Cirone, Mara
author_facet Santarelli, Roberta
Granato, Marisa
Faggioni, Alberto
Cirone, Mara
author_sort Santarelli, Roberta
collection PubMed
description We summarized the most recent findings on the role of autophagy in antiviral immune response. We described how viruses have developed strategies to subvert the autophagic process. A particular attention has been given to Epstein-Barr and Kaposi's sarcoma associated Herpesvirus, viruses studied for many years in our laboratory. These two viruses belong to γ-Herpesvirus subfamily and are associated with several human cancers. Besides the effects on the immune response, we have described how autophagy subversion by viruses may also concur to the enhancement of their replication and to viral tumorigenesis.
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spelling pubmed-44515632015-06-18 Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses Santarelli, Roberta Granato, Marisa Faggioni, Alberto Cirone, Mara J Immunol Res Review Article We summarized the most recent findings on the role of autophagy in antiviral immune response. We described how viruses have developed strategies to subvert the autophagic process. A particular attention has been given to Epstein-Barr and Kaposi's sarcoma associated Herpesvirus, viruses studied for many years in our laboratory. These two viruses belong to γ-Herpesvirus subfamily and are associated with several human cancers. Besides the effects on the immune response, we have described how autophagy subversion by viruses may also concur to the enhancement of their replication and to viral tumorigenesis. Hindawi Publishing Corporation 2015 2015-05-18 /pmc/articles/PMC4451563/ /pubmed/26090494 http://dx.doi.org/10.1155/2015/546063 Text en Copyright © 2015 Roberta Santarelli et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Santarelli, Roberta
Granato, Marisa
Faggioni, Alberto
Cirone, Mara
Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses
title Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses
title_full Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses
title_fullStr Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses
title_full_unstemmed Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses
title_short Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses
title_sort interference with the autophagic process as a viral strategy to escape from the immune control: lesson from gamma herpesviruses
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451563/
https://www.ncbi.nlm.nih.gov/pubmed/26090494
http://dx.doi.org/10.1155/2015/546063
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