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Aphthous ulcers, salivary peroxidase and stress: Are they related?

BACKGROUND: In today's high strung lifestyle, stress plays a major role on our health. Studies using ultraweak chemiluminescence have been able to demonstrate this effect, of psychological stress on the immune system, using saliva as a psychological stress marker. The impact of psychosocial fac...

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Autores principales: Kiran, Geetha C, Reginald, Bernard Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451665/
https://www.ncbi.nlm.nih.gov/pubmed/26097305
http://dx.doi.org/10.4103/0973-029X.157199
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author Kiran, Geetha C
Reginald, Bernard Ajay
author_facet Kiran, Geetha C
Reginald, Bernard Ajay
author_sort Kiran, Geetha C
collection PubMed
description BACKGROUND: In today's high strung lifestyle, stress plays a major role on our health. Studies using ultraweak chemiluminescence have been able to demonstrate this effect, of psychological stress on the immune system, using saliva as a psychological stress marker. The impact of psychosocial factors on the oral mucosal lesions of individuals found that stress can contribute to weakened immunity and increased susceptibility to infection. AIM: To study the role of salivary peroxidase (SPOx) in psychologically stressed individuals with and without the presence of aphthous ulcer. MATERIALS AND METHODS: The study involved evaluating subjects for stress, using Perceived Stress Scale. Depending on the stress scores and the presence or absence of oral aphthae, they were assigned into 3 groups of 30 each. After a thorough oral examination, individual samples of saliva was collected and subjected to microprotein estimation using a biochemical analyzer. STATISTICAL ANALYSIS USED: Analysis of variance (ANOVA) and Student's t-test. RESULTS: Decreased levels of peroxidase were found in individuals’ with aphthous ulcers, while the same was increased when no lesions were found and also on a lower stress scale. CONCLUSIONS: Our study analysis does show a variation in enzyme levels between the different groups highlighting the influence of stress on the peroxidase levels, which in turn when imbalanced, results in tissue damage, leading to aphthous formation.
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spelling pubmed-44516652015-06-19 Aphthous ulcers, salivary peroxidase and stress: Are they related? Kiran, Geetha C Reginald, Bernard Ajay J Oral Maxillofac Pathol Original Article BACKGROUND: In today's high strung lifestyle, stress plays a major role on our health. Studies using ultraweak chemiluminescence have been able to demonstrate this effect, of psychological stress on the immune system, using saliva as a psychological stress marker. The impact of psychosocial factors on the oral mucosal lesions of individuals found that stress can contribute to weakened immunity and increased susceptibility to infection. AIM: To study the role of salivary peroxidase (SPOx) in psychologically stressed individuals with and without the presence of aphthous ulcer. MATERIALS AND METHODS: The study involved evaluating subjects for stress, using Perceived Stress Scale. Depending on the stress scores and the presence or absence of oral aphthae, they were assigned into 3 groups of 30 each. After a thorough oral examination, individual samples of saliva was collected and subjected to microprotein estimation using a biochemical analyzer. STATISTICAL ANALYSIS USED: Analysis of variance (ANOVA) and Student's t-test. RESULTS: Decreased levels of peroxidase were found in individuals’ with aphthous ulcers, while the same was increased when no lesions were found and also on a lower stress scale. CONCLUSIONS: Our study analysis does show a variation in enzyme levels between the different groups highlighting the influence of stress on the peroxidase levels, which in turn when imbalanced, results in tissue damage, leading to aphthous formation. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4451665/ /pubmed/26097305 http://dx.doi.org/10.4103/0973-029X.157199 Text en Copyright: © Journal of Oral and Maxillofacial Pathology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kiran, Geetha C
Reginald, Bernard Ajay
Aphthous ulcers, salivary peroxidase and stress: Are they related?
title Aphthous ulcers, salivary peroxidase and stress: Are they related?
title_full Aphthous ulcers, salivary peroxidase and stress: Are they related?
title_fullStr Aphthous ulcers, salivary peroxidase and stress: Are they related?
title_full_unstemmed Aphthous ulcers, salivary peroxidase and stress: Are they related?
title_short Aphthous ulcers, salivary peroxidase and stress: Are they related?
title_sort aphthous ulcers, salivary peroxidase and stress: are they related?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451665/
https://www.ncbi.nlm.nih.gov/pubmed/26097305
http://dx.doi.org/10.4103/0973-029X.157199
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