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Sera from patients with active systemic lupus erythematosus patients enhance the toll-like receptor 4 response in monocyte subsets

BACKGROUND: Systemic Lupus Erythematosus (SLE) is an auto-immune disease whose complex pathogenesis remains unraveled. Here we aim to explore the inflammatory ability of SLE patients’ sera upon peripheral blood (PB) monocyte subsets and myeloid dendritic cells (mDCs) obtained from healthy donors. ME...

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Detalles Bibliográficos
Autores principales: Carvalheiro, Tiago, Gomes, Diane, Pinto, Ligia A., Inês, Luis, Lopes, Ana, Henriques, Ana, Pedreiro, Susana, Martinho, António, Trindade, Hélder, Young, Howard A., da Silva, José António Pereira, Paiva, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451730/
https://www.ncbi.nlm.nih.gov/pubmed/26038677
http://dx.doi.org/10.1186/s12950-015-0083-2