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Contrast Enhancement of the Right Ventricle during Coronary CT Angiography – Is It Necessary?

PURPOSE: It is unclear if prolonged contrast media injection, to improve right ventricular visualization during coronary CT angiography, leads to increased detection of right ventricle pathology. The purpose of this study was to evaluate right ventricle enhancement and subsequent detection of right...

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Autores principales: Kok, Madeleine, Kietselaer, Bas L. J. H., Mihl, Casper, Altintas, Sibel, Nijssen, Estelle C., Wildberger, Joachim E., Das, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451990/
https://www.ncbi.nlm.nih.gov/pubmed/26029905
http://dx.doi.org/10.1371/journal.pone.0128625
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author Kok, Madeleine
Kietselaer, Bas L. J. H.
Mihl, Casper
Altintas, Sibel
Nijssen, Estelle C.
Wildberger, Joachim E.
Das, Marco
author_facet Kok, Madeleine
Kietselaer, Bas L. J. H.
Mihl, Casper
Altintas, Sibel
Nijssen, Estelle C.
Wildberger, Joachim E.
Das, Marco
author_sort Kok, Madeleine
collection PubMed
description PURPOSE: It is unclear if prolonged contrast media injection, to improve right ventricular visualization during coronary CT angiography, leads to increased detection of right ventricle pathology. The purpose of this study was to evaluate right ventricle enhancement and subsequent detection of right ventricle disease during coronary CT angiography. MATERIALS AND METHODS: 472 consecutive patients referred for screening coronary CT angiography were retrospectively evaluated. Every patient underwent multidetector-row CT of the coronary arteries: 128x 0.6mm coll., 100-120kV, rot. time 0.28s, ref. mAs 350 and received an individualized (P3T) contrast bolus injection of iodinated contrast medium (300 mgI/ml). Patient data were analyzed to assess right ventricle enhancement (HU) and right ventricle pathology. Image quality was defined good when right ventricle enhancement >200HU, moderate when 140-200HU and poor when <140HU. RESULTS: Good image quality was found in 372 patients, moderate in 80 patients and poor in 20 patients. Mean enhancement of the right ventricle cavity was 268HU±102. Patients received an average bolus of 108±24 ml at an average peak flow rate of 6.1±2.2 ml/s. In only three out of 472 patients (0.63%) pathology of the right ventricle was found (dilatation) No other right ventricle pathology was detected. CONCLUSION: Right ventricle pathology was detected in three out of 472 patients; the dilatation observed in these three cases may have been picked up even without dedicated enhancement of the right ventricle. Based on our findings, right ventricle enhancement can be omitted during screening coronary CT angiography.
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spelling pubmed-44519902015-06-09 Contrast Enhancement of the Right Ventricle during Coronary CT Angiography – Is It Necessary? Kok, Madeleine Kietselaer, Bas L. J. H. Mihl, Casper Altintas, Sibel Nijssen, Estelle C. Wildberger, Joachim E. Das, Marco PLoS One Research Article PURPOSE: It is unclear if prolonged contrast media injection, to improve right ventricular visualization during coronary CT angiography, leads to increased detection of right ventricle pathology. The purpose of this study was to evaluate right ventricle enhancement and subsequent detection of right ventricle disease during coronary CT angiography. MATERIALS AND METHODS: 472 consecutive patients referred for screening coronary CT angiography were retrospectively evaluated. Every patient underwent multidetector-row CT of the coronary arteries: 128x 0.6mm coll., 100-120kV, rot. time 0.28s, ref. mAs 350 and received an individualized (P3T) contrast bolus injection of iodinated contrast medium (300 mgI/ml). Patient data were analyzed to assess right ventricle enhancement (HU) and right ventricle pathology. Image quality was defined good when right ventricle enhancement >200HU, moderate when 140-200HU and poor when <140HU. RESULTS: Good image quality was found in 372 patients, moderate in 80 patients and poor in 20 patients. Mean enhancement of the right ventricle cavity was 268HU±102. Patients received an average bolus of 108±24 ml at an average peak flow rate of 6.1±2.2 ml/s. In only three out of 472 patients (0.63%) pathology of the right ventricle was found (dilatation) No other right ventricle pathology was detected. CONCLUSION: Right ventricle pathology was detected in three out of 472 patients; the dilatation observed in these three cases may have been picked up even without dedicated enhancement of the right ventricle. Based on our findings, right ventricle enhancement can be omitted during screening coronary CT angiography. Public Library of Science 2015-06-01 /pmc/articles/PMC4451990/ /pubmed/26029905 http://dx.doi.org/10.1371/journal.pone.0128625 Text en © 2015 Kok et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Kok, Madeleine
Kietselaer, Bas L. J. H.
Mihl, Casper
Altintas, Sibel
Nijssen, Estelle C.
Wildberger, Joachim E.
Das, Marco
Contrast Enhancement of the Right Ventricle during Coronary CT Angiography – Is It Necessary?
title Contrast Enhancement of the Right Ventricle during Coronary CT Angiography – Is It Necessary?
title_full Contrast Enhancement of the Right Ventricle during Coronary CT Angiography – Is It Necessary?
title_fullStr Contrast Enhancement of the Right Ventricle during Coronary CT Angiography – Is It Necessary?
title_full_unstemmed Contrast Enhancement of the Right Ventricle during Coronary CT Angiography – Is It Necessary?
title_short Contrast Enhancement of the Right Ventricle during Coronary CT Angiography – Is It Necessary?
title_sort contrast enhancement of the right ventricle during coronary ct angiography – is it necessary?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451990/
https://www.ncbi.nlm.nih.gov/pubmed/26029905
http://dx.doi.org/10.1371/journal.pone.0128625
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