Resistance to the Beneficial Metabolic Effects and Hepatic Antioxidant Defense Actions of Fibroblast Growth Factor 21 Treatment in Growth Hormone-Overexpressing Transgenic Mice

Fibroblast growth factor 21 (FGF21) modulates a diverse range of biological functions, including glucose and lipid metabolism, adaptive starvation response, and energy homeostasis, but with limited mechanistic insight. FGF21 treatment has been shown to inhibit hepatic growth hormone (GH) intracellul...

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Detalles Bibliográficos
Autores principales: Boparai, Ravneet K., Arum, Oge, Miquet, Johanna G., Masternak, Michal M., Bartke, Andrzej, Khardori, Romesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451995/
https://www.ncbi.nlm.nih.gov/pubmed/26089880
http://dx.doi.org/10.1155/2015/282375

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