Using water-soluble C(60) fullerenes in anticancer therapy

Growth experiments of transplanted malignant tumors in the presence of water-soluble C(60) fullerenes were performed on groups of mice. It was found that C(60) fullerenes efficiently inhibit the growth of transplanted malignant tumors. This behavior can be explained through their high antioxidant ac...

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Detalles Bibliográficos
Autores principales: Prylutska, S. V., Burlaka, A. P., Klymenko, P. P., Grynyuk, I. I., Prylutskyy, Yu. I., Schütze, Ch., Ritter, U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2011
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452036/
https://www.ncbi.nlm.nih.gov/pubmed/26069489
http://dx.doi.org/10.1007/s12645-011-0020-x
Descripción
Sumario:Growth experiments of transplanted malignant tumors in the presence of water-soluble C(60) fullerenes were performed on groups of mice. It was found that C(60) fullerenes efficiently inhibit the growth of transplanted malignant tumors. This behavior can be explained through their high antioxidant activity and the blocking of the specific cell receptors (for example, endothelial growth factor). The findings demonstrate the possibility of using C(60) fullerenes in anticancer therapy.

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