Cargando…
Using water-soluble C(60) fullerenes in anticancer therapy
Growth experiments of transplanted malignant tumors in the presence of water-soluble C(60) fullerenes were performed on groups of mice. It was found that C(60) fullerenes efficiently inhibit the growth of transplanted malignant tumors. This behavior can be explained through their high antioxidant ac...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452036/ https://www.ncbi.nlm.nih.gov/pubmed/26069489 http://dx.doi.org/10.1007/s12645-011-0020-x |
_version_ | 1782374237635346432 |
---|---|
author | Prylutska, S. V. Burlaka, A. P. Klymenko, P. P. Grynyuk, I. I. Prylutskyy, Yu. I. Schütze, Ch. Ritter, U. |
author_facet | Prylutska, S. V. Burlaka, A. P. Klymenko, P. P. Grynyuk, I. I. Prylutskyy, Yu. I. Schütze, Ch. Ritter, U. |
author_sort | Prylutska, S. V. |
collection | PubMed |
description | Growth experiments of transplanted malignant tumors in the presence of water-soluble C(60) fullerenes were performed on groups of mice. It was found that C(60) fullerenes efficiently inhibit the growth of transplanted malignant tumors. This behavior can be explained through their high antioxidant activity and the blocking of the specific cell receptors (for example, endothelial growth factor). The findings demonstrate the possibility of using C(60) fullerenes in anticancer therapy. |
format | Online Article Text |
id | pubmed-4452036 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Springer Vienna |
record_format | MEDLINE/PubMed |
spelling | pubmed-44520362015-06-09 Using water-soluble C(60) fullerenes in anticancer therapy Prylutska, S. V. Burlaka, A. P. Klymenko, P. P. Grynyuk, I. I. Prylutskyy, Yu. I. Schütze, Ch. Ritter, U. Cancer Nanotechnol Original Paper Growth experiments of transplanted malignant tumors in the presence of water-soluble C(60) fullerenes were performed on groups of mice. It was found that C(60) fullerenes efficiently inhibit the growth of transplanted malignant tumors. This behavior can be explained through their high antioxidant activity and the blocking of the specific cell receptors (for example, endothelial growth factor). The findings demonstrate the possibility of using C(60) fullerenes in anticancer therapy. Springer Vienna 2011-08-19 2011 /pmc/articles/PMC4452036/ /pubmed/26069489 http://dx.doi.org/10.1007/s12645-011-0020-x Text en © Springer-Verlag 2011 |
spellingShingle | Original Paper Prylutska, S. V. Burlaka, A. P. Klymenko, P. P. Grynyuk, I. I. Prylutskyy, Yu. I. Schütze, Ch. Ritter, U. Using water-soluble C(60) fullerenes in anticancer therapy |
title | Using water-soluble C(60) fullerenes in anticancer therapy |
title_full | Using water-soluble C(60) fullerenes in anticancer therapy |
title_fullStr | Using water-soluble C(60) fullerenes in anticancer therapy |
title_full_unstemmed | Using water-soluble C(60) fullerenes in anticancer therapy |
title_short | Using water-soluble C(60) fullerenes in anticancer therapy |
title_sort | using water-soluble c(60) fullerenes in anticancer therapy |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452036/ https://www.ncbi.nlm.nih.gov/pubmed/26069489 http://dx.doi.org/10.1007/s12645-011-0020-x |
work_keys_str_mv | AT prylutskasv usingwatersolublec60fullerenesinanticancertherapy AT burlakaap usingwatersolublec60fullerenesinanticancertherapy AT klymenkopp usingwatersolublec60fullerenesinanticancertherapy AT grynyukii usingwatersolublec60fullerenesinanticancertherapy AT prylutskyyyui usingwatersolublec60fullerenesinanticancertherapy AT schutzech usingwatersolublec60fullerenesinanticancertherapy AT ritteru usingwatersolublec60fullerenesinanticancertherapy |