Extended blood circulation and joint accumulation of a p(HPMA-co-AzMA)-based nanoconjugate in a murine model of rheumatoid arthritis

BACKGROUND: We recently synthesized a hydrophilic polymer, poly(N-(2-hydroxypropyl)methacrylamide-co-N-(3-azidopropyl)methacrylamide), p(HPMA-co-AzMA), by RAFT polymerization using a novel azide-containing methacrylamide monomer that through a post modification strategy using click chemistry enabled...

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Detalles Bibliográficos
Autores principales: Ebbesen, Morten F, Bienk, Konrad, Deleuran, Bent W, Howard, Kenneth A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452064/
https://www.ncbi.nlm.nih.gov/pubmed/26056596
http://dx.doi.org/10.1186/2052-8426-2-29

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