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Evaluation of cytotoxicity and mechanism of apoptosis of doxorubicin using folate-decorated chitosan nanoparticles for targeted delivery to retinoblastoma

Nanoparticles are the new entities that can greatly limit the various side effects of systemic chemotherapy, and that coupled with a targeting moiety enables site-specific delivery of drugs. Folate receptors are overexpressed in retinoblastoma cells, thus these can specifically uptake the drug-loade...

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Detalles Bibliográficos
Autores principales: Parveen, Suphiya, Sahoo, Sanjeeb K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452076/
https://www.ncbi.nlm.nih.gov/pubmed/26069479
http://dx.doi.org/10.1007/s12645-010-0006-0