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BRCA/Fanconi anemia pathway implicates chemoresistance to gemcitabine in biliary tract cancer
The BRCA/Fanconi anemia (FA) pathway plays a key role in the repair of DNA double strand breaks. We focused on this pathway to clarify chemoresistance mechanisms in biliary tract cancer (BTC). We also investigated changes in the CD24(+)/44(+) population that may be involved in chemoresistance, as th...
Autores principales: | Nakashima, Shinsuke, Kobayashi, Shogo, Nagano, Hiroaki, Tomokuni, Akira, Tomimaru, Yoshito, Asaoka, Tadafumi, Hama, Naoki, Wada, Hiroshi, Kawamoto, Koichi, Marubashi, Shigeru, Eguchi, Hidetoshi, Doki, Yuichiro, Mori, Masaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452159/ https://www.ncbi.nlm.nih.gov/pubmed/25736055 http://dx.doi.org/10.1111/cas.12652 |
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