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MiR-335 Regulates Hif-1α to Reduce Cell Death in Both Mouse Cell Line and Rat Ischemic Models
Hypoxia inducible factor-1α facilitates cellular adaptation to hypoxic conditions. Hence its tight regulation is crucial in hypoxia related diseases such as cerebral ischemia. Changes in hypoxia inducible factor-1α expression upon cerebral ischemia influence the expression of its downstream genes wh...
Autores principales: | Liu, Fu Jia, Kaur, Prameet, Karolina, Dwi S., Sepramaniam, Sugunavathi, Armugam, Arunmozhiarasi, Wong, Peter T. H., Jeyaseelan, Kandiah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452242/ https://www.ncbi.nlm.nih.gov/pubmed/26030758 http://dx.doi.org/10.1371/journal.pone.0128432 |
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