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Structure of the yeast Bre1 RING domain

Monoubiquitination of histone H2B at Lys123 in yeast plays a critical role in regulating transcription, mRNA export, DNA replication, and the DNA damage response. The RING E3 ligase, Bre1, catalyzes monoubiquitination of H2B in concert with the E2 ubiquitin‐conjugating enzyme, Rad6. The crystal stru...

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Detalles Bibliográficos
Autores principales:	Kumar, Pankaj, Wolberger, Cynthia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Structure Notes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452286/ https://www.ncbi.nlm.nih.gov/pubmed/25864391 http://dx.doi.org/10.1002/prot.24812

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