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Human Mesenchymal Stem Cells Are Resistant to Paclitaxel by Adopting a Non-Proliferative Fibroblastic State

Human mesenchymal stem cell (hMSC) resistance to the apoptotic effects of chemotherapeutic drugs has been of major interest, as these cells can confer this resistance to tumor microenvironments. However, the effects of internalized chemotherapeutics upon hMSCs remain largely unexplored. In this stud...

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Detalles Bibliográficos
Autores principales:	Bosco, Dale B., Kenworthy, Rachael, Zorio, Diego A. R., Sang, Qing-Xiang Amy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452335/ https://www.ncbi.nlm.nih.gov/pubmed/26029917 http://dx.doi.org/10.1371/journal.pone.0128511

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